Amyloid pathology disrupts gliotransmitter release in astrocytes
Fig 8
Cross-correlation between individual Ca2+ and gliotransmitter release events are disrupted in astrocytic compartments with Aβ pathology.
(A) Peak cross-correlations between Ca2+ and release events become low at higher stimulation rates in astrocytes with Aβ conditions when compared to control. (B) Higher stimulation rates decrease population of docked vesicles in astrocytes with Aβ conditions when compared to control. (C) The presence of Aβ conditions shifts the relationship between peak cross-correlation and docked vesicle population.