Thalamic deep brain stimulation paradigm to reduce consciousness: Cortico-striatal dynamics implicated in mechanisms of consciousness
Fig 11
Functional connectivity increases, especially at low frequencies, just before and throughout VPC.
A, Diagram showing anatomical pathways isolated in our study. Superficial and deep cortical layers are represented by the respective light and dark regions of the labeled area. Arrow colors relate to the panel subtitle underlines featured in B-G. B-G, Time-frequency plots showing coherence differences (VPC–control stare) aligned to event onset (white vertical line) for pairs of LFPs within/between brain area(s). Color scales with the strength of the resulting t-stat. Significant clusters are outlined in black with numerical labels referenced in Table 2 for statistical details. Results are shown for the key (B) Thalamo-frontal, (C) Thalamo-parietal, (D) Cortico-striatal, (E) Subcortical, (F) Intracolumnar, and (G) Cortico-cortical feedforward (FF, Ls-Fs) and feedback (FB, Fd-Ld and Fd-Ls) pathways.