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Thalamic deep brain stimulation paradigm to reduce consciousness: Cortico-striatal dynamics implicated in mechanisms of consciousness

Fig 10

VPC and stare controls are readily decodable on a similar time-frame as changes in consciousness, and represent a clear shift in the relative importance of different frequencies.

A, Decoding accuracy (±SE) across time relative to event onset of VPC and stare controls using 25 frequency (δ, θ, α, β, γ) by brain area (CN, Ld, Ls, Fd, Fs) features. Thin saturated pink line shows period of significance when decoding accuracy is greater than chance (50%). B Mean decrease in accuracy (MDA) attributed to each model feature across time. Higher values indicate higher feature importance. D-F, MDAs further analyzed for the period of time just prior to event onset (thick blue horizontal bar in (A)) for features by (C) area and (D) frequency, and for the period of time just after VPC onset (thick red horizontal bar in (A)) for features by (E) area and (F) frequency. Bar graphs show average MDA (± SD).

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1010294.g010