Thalamic deep brain stimulation paradigm to reduce consciousness: Cortico-striatal dynamics implicated in mechanisms of consciousness
Fig 3
Example of simulated null distribution permutation test for probability analysis.
A, Example of hypothetical population, size N, consisting of 4 members and yielding observed sample, size n, consisting of the 4 members. The question to address: Is there category-specific variation in the probability of occurrence for different members of the observed samples? B, Equations demonstrating how to represent the question in A as a null hypothesis, and how to simulate samples from the population. C, Distributions (histograms) and fitted normal distributions (curves) showing the proportion of simulations yielding a given probability of member occurrence under the null hypothesis. Red lines indicate where the observed sample falls relative to the null distribution, with matching Z statistic and p-value before correction. D, Category-specific probability of occurrence where error bars indicate ± 1SD of the null distribution. * indicates statistical significance. E, Similar figure to (D), but representing the relative proportion of sample occurrences and the null hypothesis that the member proportions observed are the same as those observed in the population.