coiaf: Directly estimating complexity of infection with allele frequencies
Fig 2
Estimating the COI on simulated data.
The performance of the Variant Method (A) and Frequency Method (B) is shown for 100 simulations of a COI of 1–20 with 1,000 loci, a read depth of 200, no error added to the simulations, and no sequencing error assumed. Point size indicates density, with the red line representing the line y = x. (C) The mean absolute error for each method is shown. The black bars indicate the 95% confidence interval.