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Computational analysis of memory consolidation following inhibitory avoidance (IA) training in adult and infant rats: Critical roles of CaMKIIα and MeCP2

Fig 4

Simulated dynamics of model variables when PSI was added 25 h or 35 h post-stimulus.

Example of dynamics of BDNF protein/mRNA (A-B), C/EBPβ protein (C), pCREB (D), pCaMKIIα (E), and Sin3a binding (F), MeCP2 binding (G), HDAC2 binding (H), Tag (I), GROD (J), PP (K), and W (L), without PSI (black dashed) or with PSI added at 25 h post- stimulus (blue), or at 35 h post- stimulus (red).

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1010239.g004