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AC-PCoA: Adjustment for confounding factors using principal coordinate analysis

Fig 4

Results of SEQC data.

A: Two-dimensional plots colored by reference sample IDs after conducting PCoA, AC-PCoA and aPCoA, using four distance measures. B: MANOVA F-statistic, NMI of k-means clustering, and classification accuracy. Reference samples IDs are set to be the true label. MANOVA test, k-means clustering, and classification were conducted on two and three principal coordinates from PCoA, AC-PCoA, and aPCoA.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1010184.g004