CellDynaMo–stochastic reaction-diffusion-dynamics model: Application to search-and-capture process of mitotic spindle assembly
Table 4
Biochemical reactions at kinetochore-microtubule interface.
Enzymatic reactions (e.g., phosphorylation and dephosphorylation) and association-dissociation reactions, which involve the MT associated protein Ndc80 linking MTs with KTs, and the reaction rate constants and characteristic timescales. The subscript p = 0, 1,…,6 denotes the number of phosphate groups attached to Ndc80 and changes in the rate constants and reaction propensities for MT-Ndc80 complex dissociation.