Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis
Fig 2
Implementation of a geometric tissue-scale constitutive model of lung cancer.
A. Lung model, in which alveoli are represented as shell elements organized in a randomized hexagonal lattice. Model is 9,885 μm x 10,000 μm x 30 μm. B. Zoomed-in view of tumor and adjacent matrix under 0% and 50% globally applied stretch in x and y, displacement in z is fixed. C. Discretization of the lung model. Alveoli are represented by shell elements. The tumor is discretized using tetrahedral elements with a surrounding basement membrane of triangular elements.