Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)
Fig 6
True positive rate (TPR) and positive predictive value (PPV) before or at histopathology of genes and gene sets in known key events in DILI.
Events related to the given known key event are shown in red or blue indicating an up- or downregulation, respectively. Genes with a p-value < 0.0001 involved in known key events in DILI are additionally labelled. The background distribution of all significantly enriched genes or gene sets is shown in grey (p-value < 0.05).