Experimental guidance for discovering genetic networks through hypothesis reduction on time series
Fig 3
Panel A. Ground truth regulatory network, where sharp arrows indicate activation (or positive regulation) and blunt arrows indicate repression (or negative regulation). Panels B-D. Synthetic time series from 3 different parameterizations of a single Hill model (see Methods Section 4.4.1). Panel E. The subnetwork formed from the network in panel A of this figure by removing the node D. Panels F-H. Synthetic time series from the same parameters as in panels B-D of this figure, but excluding node D.