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Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models

Fig 10

Coupling spontaneous cells with dormant cells inside a tissue.

(A) Percentages of cells composing each category at different degrees of intercellular coupling. (B) Inet trends during diastole (top) and at TOP (bottom) with respect to different degrees of intercellular coupling for every cell category. Average value (symbol) ± standard deviation (dashed line). (C) Electrical activity of 50 cells (4th column of the 2D tissue matrix) when they are coupled with different intercellular resistances.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1010098.g010