Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models
Fig 2
Features extracted from sinoatrial node AP simulations.
A schematic AP trace is annotated with characteristic features. The full waveform is divided into the AP phase (solid line) and diastolic phase (dashed line) based on the criteria described. Critical voltages and durations are defined as labeled. Abbreviations: APA, action potential amplitude (mV); APD, action potential duration (ms); CL, cycle length (ms); DD, diastolic depolarization (ms); MDP, maximum diastolic potential (mV); OS, overshoot (mV); TOP, take off potential (mV).