Calcium modeling of spine apparatus-containing human dendritic spines demonstrates an “all-or-nothing” communication switch between the spine head and dendrite
Fig 7
In A we plot the critical RyR density against the ratio of Spine Apparatus Neck area to Spine Neck area. In Table 2 we show the values that correspond to A. In C and D we demonstrate that widening the neck diameter of a spine affects the coupling of Ca2+ to the dendritic region. In particular E indicates that neck widening causes the critical RyR density to increase.