Pairing statistics and melting of random DNA oligomers: Finding your partner in superdiverse environments
Fig 5
Theoretical predictions of melting curves, computed for DNA 8mers at 25g/L and 1M NaCl.
The green solid line stands for the melting curve predicted for a pair of complementary strands when using the energy obtained from our parametrization, with α = 0 and fCG = 0.5. The purple dashed-line and related shading are, respectively, the mean value and the standard deviation computed using the NN model over a set of 40 melting curves of distinct DNA sequences with fixed fCG = 0.5. The dotted lines are the melting curve of 8N with different values of fCG (Eq (6)), as specified in the colorbar. The solid dark red line is the ensemble melting curve θe, obtained by the average of
over the possible values of fCG (as given by Eq (7)).