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Non-linear archetypal analysis of single-cell RNA-seq data by deep autoencoders

Fig 10

Enriched GO terms and top DEGs of GEP 2 and GEP 4 in the prefrontal cortex dataset.

(a) The top 10 enriched GO biological process terms using upregulated DEGs in GEP 2. (b) The expression levels of the top 20 DEGs with the largest z-scores covaried with the inferred usage of GEP 2. (c) The top 10 enriched GO biological process terms using upregulated DEGs in GEP 4. (d) The expression levels of the top 20 DEGs of GEP4 covaried with the inferred usage of GEP 4. Cells in b and d were sorted by increasing order of the inferred cell usage of GEP 2 and GEP 4, respectively.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1010025.g010