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Non-linear archetypal analysis of single-cell RNA-seq data by deep autoencoders

Fig 6

Enriched GO terms and top DEGs of GEP 2 and GEP 7 in the pancreatic islet dataset.

(a) The top 10 enriched GO biological process terms using 26 significantly upregulated genes of GEP 2. (b) The expression levels of the top 20 DEGs of GEP 2 with the largest z-scores from the DEG test covaried with the inferred usage of GEP 2. (c) The top 10 enriched GO biological process terms using 84 significantly upregulated genes of GEP 7. (d) The top 20 DEGs of GEP 7 with the largest z-scores. Cells in b and d were sorted in increasing order based on the inferred cell usage of GEP 2 and GEP 7, respectively.

Fig 6

doi: https://doi.org/10.1371/journal.pcbi.1010025.g006