Dissecting mutational allosteric effects in alkaline phosphatases associated with different Hypophosphatasia phenotypes: An integrative computational investigation
Fig 6
Comparison of the change of four network centralities and five dynamics-based parameters, including (A)ΔDC, (B) ΔBC, (C) ΔCC, (D) ΔC, (E) MSF, (F) effectiveness, (G) sensitivity, (H) MBS, and (I) stiffness, among mutations in the control, mild, and severe groups by Wilcoxon signed ranked test.