Simulation atomic force microscopy for atomic reconstruction of biomolecular structures from resolution-limited experimental images
Fig 1
BioAFMviewer interactive interface.
Central are the synchronized molecular viewer and AFM windows which provide live simulated scanning of the loaded molecular structure in arbitrary orientations. The Assistant window (left) allows to conveniently change scanning parameters such as spatial resolution and tip shape, and to adjust the height range and color scale of the displayed simulated AFM graphics. The Toolbox provides the implemented topography analysis tools and the tool for fitting to an uploaded experimental AFM image (right). Here, the actin filament was used for demonstration.