Addressing the mean-correlation relationship in co-expression analysis
Fig 7
The impact of SpQN on transcription factor co-expression.
Data is from adipose subcutaneous from GTEx. The percent increase in the number of edges (y-axis) identified after thresholding (x-axis) the correlation matrix. (a) Edges involving transcription factors. (b) Edges between genes with protein-protein interactions, where one of the involved genes is a transcription factor. Additional tissues are depicted in Figs E and F in S1 Text.