Addressing the mean-correlation relationship in co-expression analysis
Fig 4
Spatial quantile normalization explained.
(a) A submatrix Xi,j of the correlation matrix, and its enclosing submatrix Yi,j. (b) Two directly adjacent, non-overlapping, submatrices Xi,j, Xi+1,j and their enclosing, overlapping, submatrices Yi,j, Yi+1,j. The enclosing submatrices Yi,j, Yi+1,j are used to form the empirical distribution functions , which are then applied to the non-overlapping submatrices as
.