Integrative experimental/computational approach establishes active cellular protrusion as the primary driving force of phagocytic spreading by immune cells
Fig 4
Relationship between ligand density and maximum contact area, as predicted by the Young-Dupre equation.
The adhesion energy γ, and therefore the ligand density ρIgG, can be expressed as a function of the contact area of the final spherical cap formed by a viscous droplet. The tested adhesion strengths are marked as red dots. Actual experimental values are shown for comparison. Error bars indicate standard deviation.