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The impact of the spatial heterogeneity of resistant cells and fibroblasts on treatment response

Fig 8

Cell configurations for CAF-mediated tumor growth.

Cell configurations at different times under CT-MTD (continuous MTD therapy) for all type of fibroblast configurations. Each row shows results for one type of fibroblast configuration. The blue and orange dots show the S-cells and R-cells respectively and the purple shaded areas show the fibroblast regions. Specification of the fibroblast region is shown in the section Initial and boundary conditions.

Fig 8

doi: https://doi.org/10.1371/journal.pcbi.1009919.g008