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Mapping the gene network landscape of Alzheimer’s disease through integrating genomics and transcriptomics

Fig 3

Annotations of Mammalian Phenotype Ontology on the AD network genes.

The figure shows the odds ratios and 95% confidence intervals for the 9 significantly enriched brain-related phenotypes, and one negative control phenotype (abnormal skeleton physiology). The circle size indicates the number of genes which result in that phenotype when knocked out in mice.

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1009903.g003