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Predicting drug polypharmacology from cell morphology readouts using variational autoencoder latent space arithmetic

Fig 3

Investigating the contribution of CellProfiler feature groups (by compartments and image channels) on individual MMD-VAE latent space features.

The dendrogram represents a hierarchical clustering algorithm applied to both rows and columns. Each color represents the mean contribution of each CellProfiler feature group to the given latent space feature normalized by column (see Methods for complete details).

Fig 3

doi: https://doi.org/10.1371/journal.pcbi.1009888.g003