Comparative analyses of parasites with a comprehensive database of genome-scale metabolic models
Fig 4
Reaction frequency ranges from unique to core metabolism.
Reconstructions help identify rare metabolic functions (light grey box and on histogram, in fewer than 10 reconstructions) and core parasite metabolism (dark grey box and on histogram, in more than 166 reconstructions). Example rare reactions include seven metabolic reactions that are found in only one reconstruction. Of the 45 reactions found in all reconstructions (core metabolism), most reactions correspond to ABC transporter functions for ions or phospholipids. One reaction corresponds with a tRNA synthetase and the remaining correspond to fatty acid-CoA ligases for various fatty acids.