A three-dimensional multiscale model for the prediction of thrombus growth under flow with single-platelet resolution
Fig 1
Multiscale model for thrombus growth under flow.
The multiscale simulation of thrombus growth under flow required simultaneous solutions of the instantaneous velocity field over a complex and evolving platelet boundary by LB, concentration fields of ADP and TXA2 by FVM, individual intracellular platelet state ([Ca]i) and release reactions (R) for ADP and TXA2 by NN, and all platelet positions and adhesion/detachment by LKMC.