Autocrine signaling can explain the emergence of Allee effects in cancer cell populations
Fig 5
Least squares fit of the Allee ODE-models to in vitro growth of the glioblastoma cell lines U3013MG, U3123MG and U3289MG.
Panels A-C show the best fit of the Allee model whereas D-F show the best fit for a logistic growth model (where ρ = 0). Visual inspection suggests that the Allee model outperforms the logistic model. This was confirmed using Akaike Information Criterion (see Table 2).