Inference of trajectory presence by tree dimension and subset specificity by subtree cover
Fig 7
Trajectory presence testing on 110 real single-cell datasets.
(A) ROC curves and AUC scores for TDT effect size S/N, number of leaves L and tree diameter Dm. (B) PR curves and AUC scores for the three methods. (C) The PCA plot and EMST representation of trajectory patterns in single-cell human lung adenocarcinoma cancer cell lines data. Points represent cells. Text shows p-values of each method when applied on the dataset. (D) PCA and EMST plots of a trajectory pattern in human female germline single-cell data (E) PCA and EMST plots of a trajectory pattern in planaria single-cell data. (F)–(H) PCA and EMST plots of datasets with no significant trajectory patterns.