Flux balance analysis of the ammonia-oxidizing bacterium Nitrosomonas europaea ATCC19718 unravels specific metabolic activities while degrading toxic compounds
Fig 1
(A) Comparison of shared reactions among iGC535 and template models (iHN637, iPC815, iML1515). (B) Comparison of shared genes among iGC535 and other Ne models. (C) Reactions distribution through the subsystems in the genome-scale model. (D) Electron transport chain simulated using fructose at high concentrations or HCO3- as the sole carbon source. Abbreviations: NADH16pp, NADH dehydrogenase; AMO, ammonia monooxygenase; HAO, hydroxylamine oxidoreductase; CYTEX, cytochrome exchange; Q8H2ASE, ubiquinol synthase; CYTbc1, CytCbc1 reductase using ubiquinol-8; C552oxi, cytochrome c552 oxidase; ATPS, ATP synthase; QH2, ubiquinol; Q, ubiquinone; HAM, hydroxylamine; C554red, cytochrome c554 reduced; C554ox, cytochrome c554 oxidized; c552mox, membrane cytochrome c552 oxidized; c552mred, membrane cytochrome c552 reduced; C552ox, cytochrome c552 oxidized; C552red, cytochrome c552 reduced; Fru, fructose.