Classical mathematical models for prediction of response to chemotherapy and immunotherapy
Fig 4
Fit of the exponential model and the General Bertalanffy model to unseen data.
(A) Fit (blue) of the exponential model to the full timeline of representative patients with “up”, “down” and “fluctuate” trajectories. For the same patients, the prediction (yellow) is shown which was fitted to all points except the last three data points. (B) Corresponding plot for the General Bertalanffy model. The y axis is the relative tumor volume with respect to the largest tumor in the whole dataset, shown as 10^-3.