A computationally tractable birth-death model that combines phylogenetic and epidemiological data
Fig 2
TimTam tends to overestimate the log-likelihood on larger datasets, but this tendency is small relative to the overall variability in the log-likelihoods across the simulations. (A) The log-likelihood evaluated using TimTam and the ODE approximation are in good agreement. (B) A Bland-Altman plot comparing the values from TimTam and the ODE approximation reveals that there is a small systematic difference in the methods. (C) TimTam appears to overestimate the log-likelihood on larger datasets but the relative error is small.