Controlling gene expression timing through gene regulatory architecture
Fig 3
Power-law behavior in auto-activated gene.
(A) Peak value of MFPT as a function of auto-regulation strength, α, shows a power-law behavior with approximate exponent of 0.5 irrespective of basal transcription (r0) or translation rates (b). (B) Peak MFPT for different expression thresholds have different exponents. (C)Power-law exponent of Peak MFPT versus auto-regulation strengths as a function of expression threshold. (D) The value of koff/(r0b) at the peak MFPT also follows a power law behavior with exponent slightly larger than 1. (E) The exponent again depends on threshold. (F) The value of the exponent as a function of threshold.