Modeling cortical synaptic effects of anesthesia and their cholinergic reversal
Fig 6
Effects of anesthetic concentration and simulated ACh-induced reversal on relative profiles of neuronal firing frequency.
Each panel depicts the firing frequency of each neuron in a given anesthetic/reversal state (x-axis) compared to its firing frequency in the non-anesthetic condition (0% desflurane or A1) (y-axis) A) Units recorded in the experimental data; B,C) Neurons in A-series optimized networks and reversal.