Systematic evaluation of NIPT aneuploidy detection software tools with clinically validated NIPT samples
Fig 3
Correlation between the ‘true’ (based on 20M RPS data) and low sequencing depth based FF estimates.
Pearson correlation data are shown for 20M RPS FF 0–5% estimates and estimates obtained at sequencing depths of 15M RPS (A), 10M RPS (B), 5M RPS (C), 2.5M RPS (D), and 1.25M RPS (E).