Development of an experiment-split method for benchmarking the generalization of a PTM site predictor: Lysine methylome as an example
Fig 3
The graph representation of the CNNOH model.
(A) The input sequence consists of 61 amino acids. (B) In the input layer, the input sequence is represented by a binary matrix using the One-Hot encoding. (C) The convolution layer contains two convolution sublayers and two max-pooling sublayers. D) Fully connected layer. The output matrix from the convolution layer is nonlinearly transformed to 128 representative features. E) Output layer. The modification score is calculated based on the 128 features. The details are described in the Methods section.