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Use of Raman and Raman optical activity to extract atomistic details of saccharides in aqueous solution

Fig 4

Raman/ROA spectra of M13.

Comparison of experimental (exp.) and calculated spectra of M13 disaccharide. Top left—best fit: Best fit of md1/md2/md3/md4 Raman/ROA spectra to experimental data. Top right—MD: Simulated Raman/ROA spectra obtained using structures from unbiased MD simulation (MD). Bottom—local-conformers: Calculated ensemble averaged Raman/ROA spectra of M13 disaccharide prepared in 4 distinct conformations md1/md2/md3/md4 as described in Fig 3.

Fig 4

doi: https://doi.org/10.1371/journal.pcbi.1009678.g004