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Extracting multi-way chromatin contacts from Hi-C data

Fig 6

Many-body contacts in a Gaussian polymer chain consisting of 20 sites.

(A) Two-body contact probability log₁₀(p_ij). (B) Three-body contact probability log₁₀(p_ijk) anchored at the 7-th site (k = 7). (C) Four-body contact probability log₁₀(p_ijkl) double anchored at the 6-th and 15-th sites (k = 6, l = 15). (D-F) Boost factor p_ijk/p_ij p_jk, hub-score H_ijk, and association z-score A_ijk from the viewpoint of the 7-th site.

doi: https://doi.org/10.1371/journal.pcbi.1009669.g006