Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework
Fig 9
Sobol sensitivity analysis with fixed fitness and efficiency.
For the female fertility homing drive, fitness and efficiency were both fixed at 90%. For the viability homing drive, fitness and efficiency were both fixed at 97%. For the Y-shredder, fitness and efficiency were both fixed at 99%. The models without resistance were used. “First order effects” describe the effects of varying a single parameter. “Total effects” include the first order effects of the parameter, as well as potential synergistic interactions between that parameter and one or more other parameters.