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Quantitative modeling identifies critical cell mechanics driving bile duct lumen formation

Fig 10

Simulation results compared to Model 3 with nominal parameters.

(A) Effect of a higher global cell-cell adhesion energy value. (B-C) Effect of an apical adhesion energy value equal to the global cell-cell adhesion energy (Wap = W), for Pl = 50Pa and Pl = 70Pa respectively. In the last figure, only the individual realizations are shown for clarity reasons.

Fig 10

doi: https://doi.org/10.1371/journal.pcbi.1009653.g010