Engaging biological oscillators through second messenger pathways permits emergence of a robust gastric slow-wave during peristalsis
Fig 4
Enhanced longitudinal entrainment. Synergy of electrical coupling and second messenger exchange preserve longitudinal entrainment along the entire length of the stomach.
(A1, A2 and A3) Structure of the network, when only electrical coupling is present (A1), when only exchange of second messengers is present (A2), and when both electrical coupling and exchange of second messengers are present (A3). (B) The Relative Lags for the three different cases shown in Fig 4A are measured from the last 20 cycles of respective simulations. (C) Spatiotemporal maps of SM Cell Periods in the three different cases respectively.