Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations
Fig 4
Improvement in imputation performance in an example region.
Example region on chromosome 10 where the incorporation of add-on tags lead to the increase in imputation performance. Facet grids illustrate imputation performance of the H3Africa array without any add-on tags, with random add-on tags, and with add-on tags selected under the proposed approach. Color of dots represent type of variant (existing H3Africa tags, add-on tags, or any other imputed variants.