A systems genomics approach uncovers molecular associates of RSV severity
Fig 6
Common and unique pathways in lymphocytes & nasal epithelial cells of integration models.
Sankey diagram showing the common and unique pathways among lymphocytes & nasal epithelial cells of integration model of CD4, nasal epithelial cells and microbiota (M1) and model of lymphocytes (M4). Ingenuity Pathway Analysis (IPA) was used to identify canonical pathways represented by genes associated with severity in lymphocytes and nasal epithelial cells. Pathways are shown where Fisher’s exact test p-values were less than 0.05. Red and blue indicate predicted increased or decreased pathway activation (activation z-score), respectively. The width of the flow bar is proportional to absolute value of activation z-score.