Modelling novelty detection in the thalamocortical loop
Fig 3
SSA in the thalamocortical network.
(A) Time course of the whisker oddball protocol (top), L4 population activity, AL4, (middle), and mean synaptic resources, xL4, (bottom) in standard D2 (blue traces) and deviant C2 (red) barrel. Both standard and deviant stimuli evoke comparable amplitude of PS (the first burst in response to each stimulus) due to the fast recovery of depleted resources. Conversely, late oscillations occur primarily in response to deviant stimuli. (B) L6 population activity, AL6, (top) and mean synaptic resources, xL6, (bottom) in D2 and C2 infrabarrel. The deviant stimulus generally triggers more substantial PSs than the standard because of more resource available upon presentation of the deviant than the standard. (C) Population activities of TC cells, ATC, in D2 and C2 barreloids. The deviant corticothalamic PS is always strong enough to initiate late thalamic oscillation, yet this is not the case for the standard. (D) Spike raster of thalamic neurons in D2 (blue) and C2 (red) barreloids. The transient activity of C2 RE cells in response to the first stimulation are caused by the significant cortical cross-column L6 feedback. The time axes of all plots are aligned. In the oddball paradigm, peripheral stimulus duration is 10 ms and inter-stimulus interval (ISI) is 1 s (onset-to-onset).