Attractive internuclear force drives the collective behavior of nuclear arrays in Drosophila embryos
Fig 7
Molecular basis of the Fa force field from the MFLNN model.
(A) The relationship between biological molecular dynamics and the Fa force. Each nucleus dynamically changes between five typical states during each nuclear cycle: “mitotic furrow state”, “mitotic furrow recovery state”, “flat membrane with lager membrane deformation and less myosin II state”, “actomyosin border formation with small membrane deformation state”, and “actomyosin border formation completion state”. The relationship between the states and the Fa force field is shown in the right panel. The corresponding nuclear motion process is shown in the left panel. (B) Heat maps of the calculated average cell area (the Voronoi area of each nucleus) variation relative to the original cell area (left) and the nuclear age (right) after the onset of anaphase 12.