Data-driven multi-scale mathematical modeling of SARS-CoV-2 infection reveals heterogeneity among COVID-19 patients
Fig 7
Dynamics of COVID-19 in response to a scarcity of naïve T cells and a mild exhaustion of T cells (ρ = 0.0005) (out of 100 individual runs).
a. Time course of the average ratio of infected cells. b. Time course of average cytokines. c. Time course of average effector T cells. Red and blue lines indicate different levels of naïve T cells with ([T0] = 105 cells/ml) and ([T0] = 2 × 105 cells/ml), respectively. The error bar indicates standard deviation. Other parameters were assigned default values as shown in Table A in S1 Text.