GPRuler: Metabolic gene-protein-reaction rules automatic reconstruction
Fig 4
Evaluation of GPRuler performance in the obtained mismatches when compared with ground truth GPRs.
The blue histograms on the left of each panel show the relative frequencies distribution of Jaccard indexes computed for the retrieved negative matches in all the four ground truth models. Specifically: HMRcore in Panel A; Recon3D in Panel B; Yeast 7 in Panel C; Yeast 8 in Panel D. We reported in the green histograms on the right of each panel the normalized Hamming distance between the two truth matrices of negative matches having Jaccard index of 1.