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Approximate distance correlation for selecting highly interrelated genes across datasets

Fig 1

Schematic diagram of ADC.

Single-cell gene expression data are used as an example to illustrate ADC. X and Y are data matrices with matched genes as the inputs of ADC. For each target gene, ADC selects k genes having the highest Pearson correlation coefficient with the target one to calculate the p value of DC. After that, ADC performs the BH adjustment to control the FDR and outputs the most highly interrelated genes.

Fig 1

doi: https://doi.org/10.1371/journal.pcbi.1009548.g001