Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse
Fig 8
(A) Black traces: Spontaneous, sub- and suprathreshold events recorded during a whole-cell in vivo recording of a principal neuron in the MNTB from a P52 C57BL/6J mouse [58]. Events were aligned on the start of their EPSP and (<1 mV) differences in the resting membrane potential between events were subtracted for the display. Minimum interval between events was 20 ms. Red trace: average of >1000 events. Resting potential was -64 mV. Arrow points at the small prespike. Vertical scale bar: 10 mV. Horizontal: 1 ms. (B) As (A), showing close-up of the prespike (arrow). Vertical scale bar: 0.2 mV. Horizontal: 0.2 ms.