Using ephaptic coupling to estimate the synaptic cleft resistivity of the calyx of Held synapse
Fig 7
Synapse geometry determines the profile of the cleft potential.
(A) Drawing of a radially-symmetric synapse with cleft height h and radius r. The capacitive currents will generate a cleft potential v(x) at location x. (B) Cleft voltage profile for synapses with different radii (color-coded) at the first peak in the capacitive current. The horizontal axis depicts the location from the center (0) relative to the edge (1.0). In (B), Rex is 100 Ω cm, Cm is 1 μF cm-2, and h is 30 nm.